Learn the principles of image guided and adaptive radiotherapy; understand how to implement and evaluate them in your own institution, depending on workflow and resources. This live course is organised to identify the influence of image guidance at important steps in the workflow of radiation therapy. The following items will be covered in view of in-room imaging for therapy guidance: • Image guidance required for treatment prescription • Image guidance in treatment preparation and treatment planning • Image guidance in patient set-up and target localisation during treatment • Strategies and software tools for adaptive radiotherapy • Image guidance in treatment follow-up • MR-guided radiotherapy.