The course aims to: Provide an introduction to radiation biology as applied to radiotherapy Cover the basic mechanisms of cell death/survival and the radiation response of tumours and normal tissues Explain the formulae of tissue tolerance Describe the biological basis for current approaches to the improvement of radiotherapy including novel fractionation schemes, retreatment, IMRT, modification of hypoxia, hadron therapy, combined radiotherapy/chemotherapy and biological modifiers of tumour and normal tissue effects