The emerging trends of the past few decades have transformed the external environment many organisations operate in; new technologies now influence all areas of social and work life; hyper-connectivity has overturned traditional power structures and created a global network society; complex systemic challenges have shifted expectations on how different sectors and stakeholders must work together to drive social impact. The advent of COVID-19 has further accelerated those changes, while also increasing disruption and uncertainty. While in the immediate aftermath of the pandemic many organisations, including in the cancer space, were effectively able to adapt to maintain their operations, the current uncertain context has highlighted the need of and created an opportunity for a deeper paradigm shift in the way leaders guide others and organisations pursue their missions. Through this Master course, participants will take a closer look at some of the emerging leadership and organisational challenges of today: from creating an environment attractive to talent, to developing operational resilience, from planning in the face of uncertainty, to embracing the opportunities of digital, from creating innovations for lasting social impact, to strengthening the collaborative fabric and culture within our organisations. Framing those challenges within the context of cancer control organisations, the course will combine insights from organisational and leadership experts with perspectives from cancer control leaders and practitioners to provide participants with new ideas and practical tools that can help them make their organisations future-ready now.